(HSA) protein that had been labeled with two fluorescent probes, indocyanine green (ICG) and fluorescein (FITC), respectively. These structures were coated with a monolayer of human serum albumin. Silver fractal-like structures have been grown on both silver electrodes and on glass slides. We believe that this new silver-surface preparation, which results in ultrabright and photostable fluorophores, offers a new generic technology platform for increased fluorescence signal levels, with widespread potential applications to the analytical sciences, imaging, and medical diagnostics. These results further serve to complement our recent work on the effects of nobel metal particles with fluorophores, a relatively new phenomenon we have termed both metal-enhanced fluorescence and radiative decay engineering. Five-hundred-fold enhanced fluorescence emission from fluorophore-protein coated silver fractal-like structures has been observed.
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